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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11481
Species: Mus musculus
RGD Object: Gene
Symbol: Vcam1
Name: vascular cell adhesion molecule 1
Acc ID: CHEBI:27915
Term: melamine
Definition: A trimer of cyanamide, with a 1,3,5-triazine skeleton.
Chemical ID: MESH:C011907
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vcam1increases expressionISOVCAM1 (Homo sapiens)6480464CTDmelamine results in increased expression of VCAM1 mRNAPMID:22915474
Vcam1multiple interactionsISOVCAM1 (Homo sapiens)6480464CTD1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [melamine results in increased expression of VCAM1 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [melamine results in increased expression of VCAM1 mRNA]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [melamine results in increased expression of VCAM1 mRNA]; SB 203580 inhibits the reaction [melamine results in increased expression of VCAM1 mRNA]; SN50 peptide inhibits the reaction [melamine results in increased expression of VCAM1 mRNA]PMID:22915474
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