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GENE - TERM ANNOTATION REPORT

RGD ID: 11429
Species: Mus musculus
RGD Object: Gene
Symbol: Tnf
Name: tumor necrosis factor
Acc ID: DOID:9000310
Term: Lung Injury
Definition: Damage to any compartment of the lung caused by physical, chemical, or biological agents which characteristically elicit inflammatory reaction. These inflammatory reactions can either be acute and dominated by NEUTROPHILS, or chronic and dominated by LYMPHOCYTES and MACROPHAGES.
Definition Source(s): MESH:D055370
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnf ISOTNF (Homo sapiens)11554173CTDCTD Direct Evidence: marker/mechanism|therapeuticPMID:2518282 PMID:26243812 PMID:34255241
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