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GENE - TERM ANNOTATION REPORT

RGD ID: 11429
Species: Mus musculus
RGD Object: Gene
Symbol: Tnf
Name: tumor necrosis factor
Acc ID: DOID:6364
Term: migraine
Definition: A brain disease that is characterized by moderate to severe headaches, nausea, extreme sensitivity to light and sound and intense unilaterial throbbing or pulsing. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Migraine "DO" "DO", http://www.mayoclinic.com/health/migraine-headache/DS00120 "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TnfsusceptibilityISOTNF (Homo sapiens)7240710OMIM  
Tnf ISOTNF (Homo sapiens)11554173CTDCTD Direct Evidence: marker/mechanism 
Tnf ISOTNF (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Migraine with or without aura, susceptibility to, 1PMID:25741868
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