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GENE - TERM ANNOTATION REPORT

RGD ID: 11429
Species: Mus musculus
RGD Object: Gene
Symbol: Tnf
Name: tumor necrosis factor
Acc ID: DOID:6000
Term: congestive heart failure
Definition: A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Heart_disease "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnf ISOTnf (Rattus norvegicus)14975271RGD  
TnfseverityISOTNF (Homo sapiens)7401241RGD  
TnftreatmentISOTnf (Rattus norvegicus)1580213RGD  
TnftreatmentISOTnf (Rattus norvegicus)7401242RGDassociated with Myocardial Infarction; 
Tnf ISOTNF (Homo sapiens)11554173CTDCTD Direct Evidence: marker/mechanismPMID:15135663 PMID:15231041 PMID:17337591 PMID:18034274 PMID:29959987
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