GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | increases expression | EXP | | 6480464 | CTD | 3-methyladenine results in increased expression of TNF mRNA | PMID:31513885 | Tnf | multiple interactions | EXP | | 6480464 | CTD | 3-methyladenine inhibits the reaction [anemoside B4 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]] | PMID:34051206 | Tnf | multiple interactions | ISO | TNF (Homo sapiens) | 6480464 | CTD | 3-methyladenine inhibits the reaction [[TNF protein co-treated with Resveratrol] results in increased expression of MAP1LC3B protein alternative form]; 3-methyladenine inhibits the reaction [Particulate Matter results in increased secretion of TNF protein]; 3-methyladenine inhibits the reaction [Resveratrol inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; 3-methyladenine inhibits the reaction [Resveratrol inhibits the reaction [TNF protein results in increased expression of MMP9 protein]]; 3-methyladenine inhibits the reaction [Resveratrol inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]]; [3-methyladenine co-treated with TNF protein] results in decreased expression of MAP1LC3B protein alternative form | PMID:24145604 PMID:29781141 | Tnf | multiple interactions | ISO | Tnf (Rattus norvegicus) | 6480464 | CTD | 3-methyladenine inhibits the reaction [lead acetate results in increased expression of TNF protein]; 3-methyladenine promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF protein] | PMID:31586597 PMID:32879255 | | ||||||||||||||||||||||
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