A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID:
MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
[Dietary Fats affects the susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of TNF mRNA; [Dietary Sucrose co-treated with Dietary Fats co-treated with bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of TNF mRNA; [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TNF mRNA; [Tetrachlorodibenzodioxin co-treated with TNF protein] affects the expression of CCL5 mRNA; [Tetrachlorodibenzodioxin co-treated with TNF protein] affects the expression of PF4 mRNA; AHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of TNF mRNA]; AHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of TNF protein]; AHRR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of TNF mRNA]; Colforsin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TNF mRNA]; LTB4R1 mRNA promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of TNF mRNA]; MAPK8 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of TNF protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TNF mRNA]; NFE2L2 gene mutant form promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of TNF mRNA]; PLA2G4A protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of TNF mRNA]; PTGES protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of TNF mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [[CpG ODN 1826 binds to and results in increased activity of TLR9 protein] which results in increased secretion of TNF protein]; Tetrachlorodibenzodioxin inhibits the reaction [[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased secretion of TNF protein]; Tetrachlorodibenzodioxin inhibits the reaction [Dextran Sulfate results in increased secretion of TNF protein]; Tetrachlorodibenzodioxin inhibits the reaction [TNF protein results in increased expression of AHR mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [TNF protein results in increased localization of REL protein]; Tetrachlorodibenzodioxin inhibits the reaction [TNF protein results in increased localization of RELA protein]; Tetrachlorodibenzodioxin inhibits the reaction [TNF protein results in increased localization of RELB protein]; Tetrachlorodibenzodioxin promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Tetrachlorodibenzodioxin promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Tetrachlorodibenzodioxin results in increased expression of and results in increased secretion of TNF protein; TNF protein affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of INSR protein]; TNF protein affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of IRS1 protein]; TNF protein affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of SLC2A4 protein]; U 0126 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TNF protein]
13-hydroxy-10-oxo-11-octadecenoic acid inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TNF mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TNF mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetrachlorodibenzodioxin results in increased secretion of TNF protein]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TNF mRNA]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [Tetrachlorodibenzodioxin results in increased secretion of TNF protein]; [Tetrachlorodibenzodioxin co-treated with TNF protein] results in increased expression of IL6 mRNA; [TNF protein co-treated with IFNG protein co-treated with IL1B protein] inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TNF mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased secretion of TNF protein]; Genistein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TNF mRNA]; Genistein inhibits the reaction [Tetrachlorodibenzodioxin results in increased secretion of TNF protein]
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TNF mRNA]; 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetrachlorodibenzodioxin results in increased secretion of TNF protein]; [Tetrachlorodibenzodioxin co-treated with Lipopolysaccharides] results in increased secretion of TNF protein; [Tetrachlorodibenzodioxin co-treated with TNF protein] results in increased expression of CCNA2 mRNA; AHR mutant form inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TNF protein]; AHR protein promotes the reaction [TNF protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]]; Nifedipine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TNF mRNA]; Nifedipine inhibits the reaction [Tetrachlorodibenzodioxin results in increased secretion of TNF protein]; Tetrachlorodibenzodioxin results in increased expression of and results in increased secretion of TNF protein; TNF protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; TNF protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]; TNF protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]; TNF protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]
