GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | increases expression | EXP | | 6480464 | CTD | Antimycin A results in increased expression of TNF protein | PMID:21910134 PMID:23624148 | Tnf | multiple interactions | EXP | | 6480464 | CTD | 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Antimycin A results in increased expression of and results in increased secretion of TNF protein]; 23-epi-26-deoxyactein inhibits the reaction [Antimycin A results in increased expression of TNF protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Antimycin A results in increased expression of and results in increased secretion of TNF protein]; Antimycin A inhibits the reaction [TNF protein results in increased expression of CXCL1 mRNA]; Antimycin A inhibits the reaction [TNF protein results in increased expression of TNFAIP3 mRNA]; Antimycin A inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIA protein]; Antimycin A inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]; Antimycin A results in increased expression of and results in increased secretion of TNF protein; Cyclosporine inhibits the reaction [Antimycin A results in increased expression of and results in increased secretion of TNF protein]; sciadopitysin inhibits the reaction [Antimycin A results in increased expression of TNF protein] | PMID:21381053 PMID:21910134 PMID:23624148 PMID:24316229 | Tnf | multiple interactions | ISO | TNF (Homo sapiens) | 6480464 | CTD | Antimycin A inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; Antimycin A promotes the reaction [TNF protein results in increased expression of CXCL8 mRNA]; Antimycin A promotes the reaction [TNF protein results in increased expression of CXCL8 protein] | PMID:11264281 PMID:22549761 | |
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