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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11340
Species: Mus musculus
RGD Object: Gene
Symbol: Spp1
Name: secreted phosphoprotein 1
Acc ID: CHEBI:17833
Term: gentamycin
Definition: Any of a group of aminoglycoside antibiotics produced by fermentation of some Micromonospora spp.
Chemical ID: MESH:D005839
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Spp1affects expressionISOSpp1 (Rattus norvegicus)6480464CTDGentamicins affects the expression of SPP1 mRNAPMID:20623750
Spp1increases expressionISOSpp1 (Rattus norvegicus)6480464CTDGentamicins results in increased expression of SPP1 mRNA; Gentamicins results in increased expression of SPP1 proteinPMID:11231351 PMID:11274264 PMID:15033597 PMID:17636248 PMID:18289764 PMID:20118187 PMID:20849911 PMID:22061828 PMID:26779593
Spp1multiple interactionsISOSpp1 (Rattus norvegicus)6480464CTDSodium Fluoride inhibits the reaction [Gentamicins results in increased expression of SPP1 mRNA]; Sodium Fluoride inhibits the reaction [Gentamicins results in increased expression of SPP1 protein]PMID:26779593
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