GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sod3 | multiple interactions | EXP | | 6480464 | CTD | [Streptozocin results in decreased activity of SOD3 protein] which results in increased chemical synthesis of Peroxynitrous Acid; [Streptozocin results in decreased activity of SOD3 protein] which results in increased chemical synthesis of Superoxides; Copper inhibits the reaction [Streptozocin results in decreased activity of SOD3 protein]; INS protein inhibits the reaction [Streptozocin results in decreased activity of SOD3 protein]; SOD3 gene mutant form promotes the reaction [Streptozocin results in increased chemical synthesis of Superoxides]; Streptozocin results in increased expression of and results in decreased activity of SOD3 protein | PMID:23884884 | Sod3 | decreases expression | ISO | Sod3 (Rattus norvegicus) | 6480464 | CTD | Streptozocin results in decreased expression of SOD3 mRNA; Streptozocin results in decreased expression of SOD3 protein | PMID:15821039 PMID:16973718 | Sod3 | multiple interactions | ISO | Sod3 (Rattus norvegicus) | 6480464 | CTD | cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SOD3 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SOD3 protein]]; Trientine inhibits the reaction [Streptozocin results in decreased expression of SOD3 mRNA]; Trientine inhibits the reaction [Streptozocin results in decreased expression of SOD3 protein] | PMID:15821039 PMID:16973718 | | ||||||||||||||||||||||
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