GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sod1 | affects abundance | EXP | | 6480464 | CTD | SOD1 protein affects the abundance of Ascorbic Acid | PMID:16377630 | Sod1 | increases expression | EXP | | 6480464 | CTD | Ascorbic Acid results in increased expression of SOD1 mRNA | PMID:32913121 | Sod1 | increases expression | ISO | SOD1 (Homo sapiens) | 6480464 | CTD | Ascorbic Acid results in increased expression of SOD1 mRNA | PMID:31576639 PMID:32913121 | Sod1 | multiple interactions | ISO | Sod1 (Rattus norvegicus) | 6480464 | CTD | [alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [arsenite results in increased expression of SOD1 protein]; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SOD1 protein]; Ascorbic Acid inhibits the reaction [Carbon Tetrachloride results in decreased activity of SOD1 protein]; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased activity of SOD1 protein]; Ascorbic Acid inhibits the reaction [Lead results in decreased expression of SOD1 protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased activity of SOD1 protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of SOD1 mRNA] | PMID:17822687 PMID:21344382 PMID:22056337 PMID:23470461 PMID:29663635 PMID:30676168 | Sod1 | multiple interactions | ISO | SOD1 (Homo sapiens) | 6480464 | CTD | [Ascorbic Acid co-treated with Vitamin E] results in increased expression of SOD1 mRNA; [Tretinoin co-treated with Ascorbic Acid] results in increased expression of SOD1 mRNA; Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of SOD1 mRNA]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in decreased activity of SOD1 protein] | PMID:16443354 PMID:22207723 PMID:28285367 PMID:31610155 | |
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