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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11307
Species: Mus musculus
RGD Object: Gene
Symbol: Slc2a3
Name: solute carrier family 2 (facilitated glucose transporter), member 3
Acc ID: CHEBI:17234
Term: glucose
Definition: An aldohexose used as a source of energy and metabolic intermediate.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc2a3multiple interactionsISOSlc2a3 (Rattus norvegicus)6480464CTD[Oxygen co-treated with Glucose deficiency co-treated with 2-(4-methoxyphenyl)ethyl-2-acetamido-2-deoxyglucopyranoside] results in increased expression of SLC2A3 protein; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Oxygen co-treated with Glucose deficiency co-treated with 2-(4-methoxyphenyl)ethyl-2-acetamido-2-deoxyglucopyranoside] results in increased expression of SLC2A3 protein]PMID:24726522
Slc2a3multiple interactionsISOSLC2A3 (Homo sapiens)6480464CTD[INS protein co-treated with Glucose] results in decreased expression of SLC2A3 protein; Glucose inhibits the reaction [SLC2A3 protein results in increased transport of Deoxyglucose]; Glucose inhibits the reaction [SLC2A3 protein results in increased transport of Galactose]; Kynurenic Acid inhibits the reaction [[INS protein co-treated with Glucose] results in decreased expression of SLC2A3 protein]PMID:28951307 PMID:8457197
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