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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11276
Species: Mus musculus
RGD Object: Gene
Symbol: Ccl3
Name: C-C motif chemokine ligand 3
Acc ID: CHEBI:53063
Term: 2,4,6-trinitrobenzenesulfonic acid
Definition: The arenesulfonic acid that is benzenesulfonic acid with three nitro substituents in the 2-, 4- and 6-positions.
Chemical ID: MESH:D014302
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccl3increases expressionEXP 6480464CTDTrinitrobenzenesulfonic Acid results in increased expression of CCL3 proteinPMID:21599020 PMID:23596210
Ccl3multiple interactionsEXP 6480464CTD[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; [Rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; cholan-2,3,24-tryl-2,3,24-trisulfate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; Rifaximin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]PMID:21599020 PMID:23596210
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