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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11180
Species: Mus musculus
RGD Object: Gene
Symbol: Psmb9
Name: proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
Acc ID: CHEBI:41879
Term: dexamethasone
Definition: A fluorinated steroid that is 9-fluoropregna-1,4-diene substituted by hydroxy groups at positions 11, 17 and 21, a methyl group at position 16 and oxo groups at positions 3 and 20. It is a synthetic member of the class of glucocorticoids.
Chemical ID: MESH:D003907
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Psmb9decreases expressionISOPSMB9 (Homo sapiens)6480464CTDDexamethasone results in decreased expression of PSMB9 mRNAPMID:31209803
Psmb9multiple interactionsISOPSMB9 (Homo sapiens)6480464CTDN-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Dexamethasone results in decreased expression of PSMB9 mRNA]PMID:31209803
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