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GENE - TERM ANNOTATION REPORT

RGD ID: 11103
Species: Mus musculus
RGD Object: Gene
Symbol: Pik3r1
Name: phosphoinositide-3-kinase regulatory subunit 1
Acc ID: GO:0005942
Term: phosphatidylinositol 3-kinase complex
Definition: A protein complex capable of phosphatidylinositol 3-kinase activity and containing subunits of any phosphatidylinositol 3-kinase (PI3K) enzyme. These complexes are divided in three classes (called I, II and III) that differ for their presence across taxonomic groups and for the type of their constituents. Catalytic subunits of phosphatidylinositol 3-kinase enzymes are present in all 3 classes; regulatory subunits of phosphatidylinositol 3-kinase enzymes are present in classes I and III; adaptor proteins have been observed in class II complexes and may be present in other classes too.
Definition Source(s): GOC:bf, PMID:24587488
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pik3r1 ISOPik3r1 (Rattus norvegicus)9068941RGD PMID:12882977 PMID:20236230 REF_RGD_ID:4107732 REF_RGD_ID:4144086
Pik3r1part_ofIBAPANTHER:PTN000806614 or FB:FBgn0020622 or UniProtKB:P23727 or UniProtKB:O00459 or Pik3r1 (Rattus norvegicus) or MGI:109277 or UniProtKB:P27986 or WB:WBGene000000012290270GO_Central GO_REF:0000033
Pik3r1part_ofISOPik3r1 (Rattus norvegicus)2290270MGI GO_REF:0000096 MGI:4417868
Pik3r1part_ofTAS 2290270MGI PMID:9988280

PMID:9988280
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