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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10996
Species: Mus musculus
RGD Object: Gene
Symbol: Nos2
Name: nitric oxide synthase 2, inducible
Acc ID: CHEBI:27568
Term: selenium atom
Definition: A chalcogen that has formula Se.
Chemical ID: MESH:D012643
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nos2multiple interactionsEXP 6480464CTD[Drugs, Chinese Herbal co-treated with Selenium] results in decreased expression of NOS2 mRNA; [Selenium inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 mRNA]] which results in decreased chemical synthesis of Nitric Oxide; Selenium inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 mRNA]; Selenium inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Selenium inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]PMID:14734799 PMID:17630198 PMID:24626144
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