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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10996
Species: Mus musculus
RGD Object: Gene
Symbol: Nos2
Name: nitric oxide synthase 2, inducible
Acc ID: CHEBI:16794
Term: scopolamine
Definition: A tropane alkaloid that is the (S)-tropic acid ester of 6beta,7beta-epoxy-1alphaH,5alphaH-tropan-3alpha-ol.
Chemical ID: MESH:D012601
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nos2increases expressionEXP 6480464CTDScopolamine results in increased expression of NOS2 proteinPMID:26408985 PMID:31077737
Nos2multiple interactionsEXP 6480464CTDacanthoside B inhibits the reaction [Scopolamine results in increased expression of NOS2 protein]; Serotonin analog inhibits the reaction [Scopolamine results in increased expression of NOS2 protein]; Tacrine inhibits the reaction [Scopolamine results in increased expression of NOS2 protein]PMID:26408985 PMID:31077737
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