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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10975
Species: Mus musculus
RGD Object: Gene
Symbol: Nfkbia
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
Acc ID: CHEBI:28741
Term: sodium fluoride
Definition: A metal fluoride salt with a Na(+) counterion.
Chemical ID: MESH:D012969
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfkbiaaffects expressionISONFKBIA (Homo sapiens)6480464CTDSodium Fluoride affects the expression of NFKBIA mRNAPMID:28012895
Nfkbiamultiple interactionsISONFKBIA (Homo sapiens)6480464CTDCurcumin inhibits the reaction [Sodium Fluoride results in increased degradation of NFKBIA protein]; protocatechuic acid methyl ester inhibits the reaction [Sodium Fluoride affects the expression of NFKBIA mRNA]; Sodium Fluoride results in increased degradation of and results in increased phosphorylation of NFKBIA proteinPMID:25540590 PMID:28012895
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