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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10916
Species: Mus musculus
RGD Object: Gene
Symbol: Mpo
Name: myeloperoxidase
Acc ID: CHEBI:28939
Term: N-acetyl-L-cysteine
Definition: An N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine.
Chemical ID: MESH:D000111
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mpomultiple interactionsEXP 6480464CTDAcetylcysteine inhibits the reaction [arachidonyl-2-chloroethylamide results in increased activity of MPO protein]PMID:32033504
Mpomultiple interactionsISOMPO (Homo sapiens)6480464CTD[MPO protein co-treated with XDH protein co-treated with Acetaldehyde] promotes the reaction [Serotonin binds to Acetylcysteine]; Acetylcysteine promotes the reaction [[MPO protein results in increased oxidation of dibromoacetonitrile] which results in increased chemical synthesis of Cyanides]; Acetylcysteine promotes the reaction [MPO protein results in increased oxidation of dibromoacetonitrile]PMID:23009681 PMID:25614581
Mpomultiple interactionsISOMpo (Rattus norvegicus)6480464CTDAcetylcysteine inhibits the reaction [Ethanol results in increased activity of MPO protein]; Acetylcysteine inhibits the reaction [Gentamicins results in increased activity of MPO protein]; Acetylcysteine inhibits the reaction [Malathion results in increased activity of MPO protein]; Acetylcysteine inhibits the reaction [Methotrexate results in increased expression of MPO protein]; Acetylcysteine inhibits the reaction [Nicotine results in increased activity of MPO protein]; Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased activity of MPO protein]]; Acetylcysteine inhibits the reaction [Paraquat results in increased activity of MPO protein]; Acetylcysteine inhibits the reaction [Smoke results in increased activity of MPO protein]; Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased activity of MPO protein]]; Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased activity of MPO protein]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased activity of MPO protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat results in increased activity of MPO protein]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased activity of MPO protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate results in increased activity of MPO protein]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased activity of MPO protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat results in increased activity of MPO protein]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased activity of MPO protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased activity of MPO protein]]PMID:11470263 PMID:17216608 PMID:17603938 PMID:20885979 PMID:22664789 PMID:24810974 PMID:25724285
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