GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mpo | decreases activity | ISO | Mpo (Rattus norvegicus) | 6480464 | CTD | Nicotine results in decreased activity of MPO protein | PMID:15976189 | Mpo | increases activity | ISO | Mpo (Rattus norvegicus) | 6480464 | CTD | Nicotine results in increased activity of MPO protein | PMID:17216608 | Mpo | multiple interactions | ISO | Mpo (Rattus norvegicus) | 6480464 | CTD | Acetylcysteine inhibits the reaction [Nicotine results in increased activity of MPO protein]; erdosteine inhibits the reaction [Nicotine results in increased activity of MPO protein]; Nicotine inhibits the reaction [Acetic Acid results in increased activity of MPO protein]; Vitamin E inhibits the reaction [Nicotine results in increased activity of MPO protein] | PMID:17216608 PMID:23810507 | |
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