GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Jun | increases expression | EXP | | 6480464 | CTD | Glucose results in increased expression of JUN mRNA | PMID:17178593 | Jun | multiple interactions | EXP | | 6480464 | CTD | Glucose inhibits the reaction [IL1B protein results in increased phosphorylation of JUN protein] | PMID:30098273 | Jun | affects localization | ISO | Jun (Rattus norvegicus) | 6480464 | CTD | Glucose affects the localization of JUN protein | PMID:20542118 | Jun | increases expression | ISO | Jun (Rattus norvegicus) | 6480464 | CTD | Glucose results in increased expression of JUN mRNA | PMID:11123204 PMID:11557636 | Jun | increases expression | ISO | JUN (Homo sapiens) | 6480464 | CTD | Glucose results in increased expression of JUN protein | PMID:16600694 | Jun | increases phosphorylation | ISO | Jun (Rattus norvegicus) | 6480464 | CTD | Glucose results in increased phosphorylation of JUN protein | PMID:16572112 PMID:19861503 | Jun | increases phosphorylation | ISO | JUN (Homo sapiens) | 6480464 | CTD | Glucose results in increased phosphorylation of JUN protein | PMID:19132243 | Jun | multiple interactions | ISO | Jun (Rattus norvegicus) | 6480464 | CTD | Dactinomycin inhibits the reaction [Glucose results in increased expression of JUN mRNA]; diphenyliodonium inhibits the reaction [Glucose results in increased phosphorylation of JUN protein]; Quercetin inhibits the reaction [Glucose affects the localization of JUN protein]; Superoxides affects the reaction [Glucose results in increased phosphorylation of JUN protein] | PMID:11123204 PMID:16572112 PMID:20542118 | Jun | multiple interactions | ISO | JUN (Homo sapiens) | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased phosphorylation of JUN protein]; [Glucose co-treated with Lipopolysaccharides] results in increased expression of JUN protein; Aspirin inhibits the reaction [Glucose results in increased expression of JUN protein]; Clofibrate inhibits the reaction [Glucose results in increased expression of JUN protein]; Fenofibrate inhibits the reaction [Glucose results in increased expression of JUN protein]; GLO1 inhibits the reaction [Glucose promotes the reaction [JUN protein binds to HMGB1 promoter]]; GLO1 inhibits the reaction [Glucose promotes the reaction [JUN protein binds to S100A12 promoter]]; GLO1 inhibits the reaction [Glucose promotes the reaction [JUN protein binds to S100A8 promoter]]; Glucose promotes the reaction [JUN protein binds to HMGB1 promoter]; Glucose promotes the reaction [JUN protein binds to MMP9 promoter]; Glucose promotes the reaction [JUN protein binds to S100A12 promoter]; Glucose promotes the reaction [JUN protein binds to S100A8 promoter]; JUN promotes the reaction [Glucose results in increased expression of HMGB1 mRNA]; JUN promotes the reaction [Glucose results in increased expression of S100A12 mRNA]; JUN promotes the reaction [Glucose results in increased expression of S100A8 mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Glucose promotes the reaction [JUN protein binds to MMP9 promoter]]; PARP1 protein affects the reaction [Glucose promotes the reaction [JUN protein binds to MMP9 promoter]]; SB 203580 inhibits the reaction [Glucose results in increased phosphorylation of JUN protein] | PMID:16600694 PMID:18180316 PMID:19132243 PMID:19833897 PMID:28478229 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |