GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il6 | multiple interactions | ISO | IL6 (Homo sapiens) | 6480464 | CTD | [IL6 protein results in increased expression of NCOA2 protein] which results in decreased susceptibility to bicalutamide; bicalutamide inhibits the reaction [Dihydrotestosterone inhibits the reaction [BCG Vaccine results in increased expression of IL6 mRNA]]; bicalutamide inhibits the reaction [Dihydrotestosterone inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; bicalutamide inhibits the reaction [Dihydrotestosterone inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]]; bicalutamide inhibits the reaction [IL6 protein results in increased expression of KLK3 mRNA] | PMID:11410519 PMID:14532843 PMID:16317058 PMID:19240160 | |
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