GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il6 | increases expression | ISO | Il6 (Rattus norvegicus) | 6480464 | CTD | Aluminum results in increased expression of IL6 protein | PMID:27368151 | Il6 | multiple interactions | ISO | IL6 (Homo sapiens) | 6480464 | CTD | [Zinc co-treated with Aluminum] results in increased expression of IL6 protein; [Zinc co-treated with Copper co-treated with Aluminum] results in increased expression of IL6 protein | PMID:27816692 | Il6 | multiple interactions | ISO | Il6 (Rattus norvegicus) | 6480464 | CTD | [Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese] results in increased expression of IL6 protein; [Cadmium co-treated with Aluminum co-treated with Fluorides] results in increased expression of IL6 protein; Berberine inhibits the reaction [[Cadmium co-treated with Aluminum co-treated with Fluorides] results in increased expression of IL6 protein]; caffeic acid inhibits the reaction [Aluminum results in increased expression of IL6 protein] | PMID:27368151 PMID:29170048 PMID:37415728 | | ||||||||||||||||||||||
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