GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il6 | decreases secretion | ISO | IL6 (Homo sapiens) | 6480464 | CTD | Dimethyl Sulfoxide results in decreased secretion of IL6 protein | PMID:24296301 | Il6 | multiple interactions | ISO | IL6 (Homo sapiens) | 6480464 | CTD | Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of IL6 protein]; Dimethyl Sulfoxide inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL6 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of IL6 protein] | PMID:10022265 PMID:21878375 PMID:9378980 | Il6 | multiple interactions | ISO | Il6 (Rattus norvegicus) | 6480464 | CTD | [lipopolysaccharide, E coli O55-B5 co-treated with Dimethyl Sulfoxide] results in increased expression of IL6 protein; Dimethyl Sulfoxide inhibits the reaction [sodium arsenite results in increased expression of IL6 mRNA] | PMID:15689417 PMID:37365769 | | ||||||||||||||||||||||
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