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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10796
Species: Mus musculus
RGD Object: Gene
Symbol: Il4
Name: interleukin 4
Acc ID: CHEBI:6842
Term: methoxychlor
Definition: An organochlorine insecticide that has formula C16H15Cl3O2.
Chemical ID: MESH:D008731
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il4increases expressionEXP 6480464CTDMethoxychlor results in increased expression of IL4 mRNA; Methoxychlor results in increased expression of IL4 proteinPMID:22842586
Il4multiple interactionsEXP 6480464CTD[Methoxychlor co-treated with Antigens, Dermatophagoides] affects the expression of IL4 protein; Methoxychlor promotes the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL4 protein]PMID:21864637 PMID:30017638
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