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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10796
Species: Mus musculus
RGD Object: Gene
Symbol: Il4
Name: interleukin 4
Acc ID: CHEBI:53050
Term: trimellitic anhydride
Definition: A 2-benzofuran compound having oxo groups at the 1- and 3-positions and a carboxy substituent at the 5-position; the cyclic anhydride formed from the carboxy groups at the 1- and 2-positions of trimellitic acid.
Chemical ID: MESH:C015559
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il4affects expressionEXP 6480464CTDtrimellitic anhydride affects the expression of IL4 mRNAPMID:22302311
Il4increases expressionEXP 6480464CTDtrimellitic anhydride results in increased expression of IL4 mRNA; trimellitic anhydride results in increased expression of IL4 proteinPMID:10637130 PMID:11708898 PMID:12884401 PMID:14599759 PMID:19042193 PMID:19042947 PMID:19422874 PMID:20219652 PMID:22381623 PMID:29233007
Il4increases secretionEXP 6480464CTDtrimellitic anhydride results in increased secretion of IL4 proteinPMID:15588915
Il4increases expressionISOIL4 (Homo sapiens)6480464CTDtrimellitic anhydride results in increased expression of IL4 mRNAPMID:21252390
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