GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il1b | decreases expression | EXP | | 6480464 | CTD | Bezafibrate results in decreased expression of IL1B mRNA | PMID:16574099 | Il1b | multiple interactions | EXP | | 6480464 | CTD | Bezafibrate inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of IL1B mRNA] | PMID:18513333 | Il1b | decreases expression | ISO | Il1b (Rattus norvegicus) | 6480464 | CTD | Bezafibrate results in decreased expression of IL1B protein | PMID:12657956 | Il1b | increases expression | ISO | Il1b (Rattus norvegicus) | 6480464 | CTD | Bezafibrate results in increased expression of IL1B protein | PMID:12704018 | Il1b | multiple interactions | ISO | Il1b (Rattus norvegicus) | 6480464 | CTD | Bezafibrate results in decreased susceptibility to [IFNG protein co-treated with IL1B protein] | PMID:20631892 | Il1b | multiple interactions | ISO | IL1B (Homo sapiens) | 6480464 | CTD | Bezafibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Bezafibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Bezafibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Bezafibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; Bezafibrate promotes the reaction [IL1B protein results in increased expression of NPHS1 mRNA] | PMID:16288986 PMID:32613381 | | ||||||||||||||||||||||
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