GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il1b | decreases expression | EXP | | 6480464 | CTD | Arsenic results in decreased expression of IL1B mRNA; Arsenic results in decreased expression of IL1B protein | PMID:19654921 | Il1b | increases expression | EXP | | 6480464 | CTD | Arsenic results in increased expression of IL1B mRNA; Arsenic results in increased expression of IL1B protein | PMID:10828279 PMID:31309260 | Il1b | multiple interactions | EXP | | 6480464 | CTD | [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Dietary Fats] results in increased expression of IL1B protein; [sodium arsenite results in increased abundance of Arsenic] inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; [sodium arsenite results in increased abundance of Arsenic] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of IL1B protein; [sodium arsenite results in increased abundance of Arsenic] which results in increased secretion of IL1B protein | PMID:30889423 PMID:31238026 PMID:32226249 PMID:33049506 | Il1b | affects expression | ISO | IL1B (Homo sapiens) | 6480464 | CTD | Arsenic affects the expression of IL1B protein | PMID:20940111 | Il1b | decreases expression | ISO | IL1B (Homo sapiens) | 6480464 | CTD | Arsenic results in decreased expression of IL1B mRNA | PMID:16835338 | Il1b | increases expression | ISO | Il1b (Rattus norvegicus) | 6480464 | CTD | Arsenic results in increased expression of IL1B protein | PMID:24348802 PMID:36850985 | Il1b | increases expression | ISO | IL1B (Homo sapiens) | 6480464 | CTD | Arsenic results in increased expression of IL1B mRNA | PMID:11134558 PMID:12928151 PMID:19945496 | Il1b | multiple interactions | ISO | Il1b (Rattus norvegicus) | 6480464 | CTD | 4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of IL1B protein]; [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of IL1B mRNA; [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of IL1B protein; Grape Seed Extract inhibits the reaction [Arsenic results in increased expression of IL1B protein]; nobiletin inhibits the reaction [Arsenic results in increased expression of IL1B protein]; zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of IL1B mRNA] | PMID:24348802 PMID:35993674 PMID:36822304 PMID:36850985 | Il1b | multiple interactions | ISO | IL1B (Homo sapiens) | 6480464 | CTD | [bafilomycin A1 co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of IL1B protein; [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of IL1B protein | PMID:32645460 | | ||||||||||||||||||||||
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