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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10789
Species: Mus musculus
RGD Object: Gene
Symbol: Il1a
Name: interleukin 1 alpha
Acc ID: CHEBI:35176
Term: zinc sulfate
Definition: A metal sulfate compound having zinc(2+) as the counterion.
Chemical ID: MESH:D019287
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1adecreases expressionISOIL1A (Homo sapiens)6480464CTDZinc Sulfate results in decreased expression of IL1A mRNAPMID:22722935
Il1amultiple interactionsISOIL1A (Homo sapiens)6480464CTDIL1A protein promotes the reaction [Zinc Sulfate results in increased expression of MT1G mRNA]; Zinc Sulfate inhibits the reaction [TNF protein results in increased expression of IL1A mRNA]; Zinc Sulfate promotes the reaction [IL1A protein results in increased expression of CXCL8 mRNA]PMID:22722935
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