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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10774
Species: Mus musculus
RGD Object: Gene
Symbol: Igfbp3
Name: insulin-like growth factor binding protein 3
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Igfbp3increases expressionEXP 6480464CTDTretinoin results in increased expression of IGFBP3 mRNAPMID:16604517
Igfbp3multiple interactionsEXP 6480464CTD[bisphenol F co-treated with Tretinoin] results in decreased expression of IGFBP3 mRNAPMID:30951980
Igfbp3increases expressionISOIGFBP3 (Homo sapiens)6480464CTDTretinoin results in increased expression of IGFBP3 mRNAPMID:15982314 PMID:16012519 PMID:16480812 PMID:16951191 PMID:21934132 PMID:23830798
Igfbp3multiple interactionsISOIgfbp3 (Rattus norvegicus)6480464CTDTretinoin affects the reaction [Oxygen affects the secretion of IGFBP3 protein]PMID:16055936
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