GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Igf1 | multiple interactions | EXP | | 6480464 | CTD | [picropodophyllin co-treated with IGF1 protein] results in increased expression of TNF mRNA; [picropodophyllin co-treated with Lipopolysaccharides] inhibits the reaction [IGF1 protein results in decreased expression of IL1B mRNA]; [picropodophyllin co-treated with Lipopolysaccharides] inhibits the reaction [IGF1 protein results in decreased expression of IL6 mRNA]; [picropodophyllin co-treated with Lipopolysaccharides] inhibits the reaction [IGF1 protein results in decreased expression of TLR4 mRNA]; [picropodophyllin co-treated with Lipopolysaccharides] inhibits the reaction [IGF1 protein results in decreased expression of TNF mRNA]; picropodophyllin inhibits the reaction [IGF1 protein results in decreased expression of TLR4 mRNA]; picropodophyllin inhibits the reaction [IGF1 protein results in increased expression of IL1B mRNA]; picropodophyllin promotes the reaction [IGF1 protein results in increased expression of IL6 mRNA] | PMID:21371294 | | ||||||||||||||||||||||
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