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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10717
Species: Mus musculus
RGD Object: Gene
Symbol: Hmox1
Name: heme oxygenase 1
Acc ID: CHEBI:3179
Term: bromobenzene
Definition: The simplest member of the class of bromobenzenes, that is benzene in which a single hydrogen has been substituted by a bromine. A liquid at room temperature (m.p. -30degreeC; b.p.760 156degreeC), it is used as a solvent, particularly for large-scale crystallisations, and for the introduction of phenyl groups in organic synthesis.
Chemical ID: MESH:C032036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hmox1increases expressionEXP 6480464CTDbromobenzene results in increased expression of HMOX1 proteinPMID:18078705
Hmox1increases expressionISOHmox1 (Rattus norvegicus)6480464CTDbromobenzene results in increased expression of HMOX1 mRNA; bromobenzene results in increased expression of HMOX1 proteinPMID:12628495 PMID:15056800 PMID:15976192 PMID:32479839 PMID:3343248
Hmox1multiple interactionsISOHmox1 (Rattus norvegicus)6480464CTD[bromobenzene co-treated with EGLN1 mutant form] results in increased expression of HMOX1 mRNAPMID:24190904
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