GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hmox1 | decreases expression | EXP | | 6480464 | CTD | methylmercuric chloride results in decreased expression of HMOX1 protein | PMID:33301842 PMID:33338554 | Hmox1 | increases expression | EXP | | 6480464 | CTD | methylmercuric chloride results in increased expression of HMOX1 mRNA | PMID:20402460 PMID:30769081 PMID:36245390 | Hmox1 | multiple interactions | EXP | | 6480464 | CTD | [GHRL protein co-treated with methylmercuric chloride] results in decreased expression of HMOX1 protein; Docosahexaenoic Acids promotes the reaction [methylmercuric chloride results in increased expression of HMOX1 mRNA]; Eicosapentaenoic Acid inhibits the reaction [Docosahexaenoic Acids promotes the reaction [methylmercuric chloride results in increased expression of HMOX1 mRNA]]; Eicosapentaenoic Acid promotes the reaction [methylmercuric chloride results in increased expression of HMOX1 mRNA]; LEP protein affects the reaction [methylmercuric chloride results in decreased expression of HMOX1 protein]; methylmercuric chloride promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of HMOX1 protein]; Tetrachlorodibenzodioxin promotes the reaction [methylmercuric chloride results in increased expression of HMOX1 mRNA] | PMID:30769081 PMID:33301842 PMID:33338554 PMID:36245390 | Hmox1 | increases expression | ISO | Hmox1 (Rattus norvegicus) | 6480464 | CTD | methylmercuric chloride results in increased expression of HMOX1 mRNA; methylmercuric chloride results in increased expression of HMOX1 protein | PMID:27298056 PMID:28736149 PMID:32061141 PMID:36813253 | Hmox1 | increases expression | ISO | HMOX1 (Homo sapiens) | 6480464 | CTD | methylmercuric chloride results in increased expression of HMOX1 mRNA; methylmercuric chloride results in increased expression of HMOX1 protein | PMID:27729293 PMID:28001369 PMID:34328791 | Hmox1 | multiple interactions | ISO | Hmox1 (Rattus norvegicus) | 6480464 | CTD | [methylmercuric chloride affects the localization of NFE2L2 protein] which results in increased expression of HMOX1 mRNA; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of HMOX1 protein]; Thioctic Acid inhibits the reaction [methylmercuric chloride results in increased expression of HMOX1 mRNA]; Thioctic Acid inhibits the reaction [methylmercuric chloride results in increased expression of HMOX1 protein] | PMID:20421342 PMID:27298056 PMID:32061141 PMID:36813253 | | ||||||||||||||||||||||
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