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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10717
Species: Mus musculus
RGD Object: Gene
Symbol: Hmox1
Name: heme oxygenase 1
Acc ID: CHEBI:81584
Term: 2,2',4,4'-Tetrabromodiphenyl ether
Definition: An organobromine compound that has formula C12H6Br4O.
Chemical ID: MESH:C511295
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hmox1multiple interactionsEXP 6480464CTD[Flame Retardants results in increased abundance of 2,2',4,4'-tetrabromodiphenyl ether] which results in increased expression of HMOX1 mRNAPMID:38995820
Hmox1increases expressionISOHMOX1 (Homo sapiens)6480464CTD2,2',4,4'-tetrabromodiphenyl ether results in increased expression of HMOX1 mRNAPMID:25305463 PMID:26808241 PMID:31173147
Hmox1multiple interactionsISOHMOX1 (Homo sapiens)6480464CTD2,2',4,4'-tetrabromodiphenyl ether promotes the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA]PMID:25305463
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