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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10708
Species: Mus musculus
RGD Object: Gene
Symbol: Hgf
Name: hepatocyte growth factor
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hgfdecreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of HGF mRNAPMID:22666406
Hgfincreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of HGF mRNAPMID:12167310 PMID:15667827 PMID:21167638
Hgfmultiple interactionsEXP 6480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of HGF mRNAPMID:17942748
Hgfaffects expressionISOHgf (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of HGF mRNAPMID:34747641
Hgfaffects expressionISOHGF (Homo sapiens)6480464CTDTetrachlorodibenzodioxin affects the expression of HGF mRNAPMID:22298810
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