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GENE - TERM ANNOTATION REPORT

RGD ID: 10700
Species: Mus musculus
RGD Object: Gene
Symbol: Gstt1
Name: glutathione S-transferase, theta 1
Acc ID: GO:0006749
Term: glutathione metabolic process
Definition: The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle.
Definition Source(s): ISBN:0198506732
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gstt1involved_inIBAPANTHER:PTN001679972 or FB:FBgn0050000 or FB:FBgn0050005 or UniProtKB:P30711 or Gstt1 (Rattus norvegicus) or MGI:107379 or FB:FBgn0031117 or MGI:2143526 or Gstt2 (Rattus norvegicus)2290270GO_Central GO_REF:0000033
Gstt1acts_upstream_of_or_withinIDA 2290270MGI PMID:12038961 PMID:8670055 PMID:9854036

PMID:12038961 PMID:8670055 PMID:9854036
Gstt1acts_upstream_of_or_withinIMPMGI:38280882290270MGI PMID:17827337

PMID:17827337
Gstt1involved_inISOGstt1 (Rattus norvegicus)2290270MGI GO_REF:0000096 MGI:4417868
Gstt1involved_inISOUniProtKB:P307112290270MGI GO_REF:0000119 MGI:4834177
Gstt1involved_inIDA 2290270UniProt MGI:4836147 PMID:20097269

MGI:4836147 PMID:20097269
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