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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10696
Species: Mus musculus
RGD Object: Gene
Symbol: Gsta2
Name: glutathione S-transferase, alpha 2 (Yc2)
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gsta2decreases expressionEXP 6480464CTDDiethylnitrosamine results in decreased expression of GSTA2 mRNAPMID:24535843
Gsta2multiple interactionsISOGsta2 (Rattus norvegicus)6480464CTD[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of GSTA2 mRNA; [Copper co-treated with Diethylnitrosamine co-treated with Iron] results in decreased expression of GSTA2 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of GSTA2 mRNA; [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GSTA2 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTA2 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of GSTA2 mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GSTA2 mRNA; [Mastic Resin co-treated with Diethylnitrosamine] results in increased expression of GSTA2 mRNA; [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of GSTA2 proteinPMID:14656948 PMID:16158176 PMID:18253720 PMID:18544905 PMID:18775883 PMID:18977376 PMID:20302851 PMID:20935162 PMID:28943392
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