GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gpx1 | affects expression | ISO | Gpx1 (Rattus norvegicus) | 6480464 | CTD | Amiodarone affects the expression of GPX1 mRNA | PMID:19483382 | Gpx1 | decreases expression | ISO | GPX1 (Homo sapiens) | 6480464 | CTD | Amiodarone results in decreased expression of GPX1 mRNA | PMID:34434487 | Gpx1 | multiple interactions | ISO | GPX1 (Homo sapiens) | 6480464 | CTD | ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of GPX1 mRNA]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of GPX1 mRNA]] | PMID:34434487 | |
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