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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10681
Species: Mus musculus
RGD Object: Gene
Symbol: Gpx1
Name: glutathione peroxidase 1
Acc ID: CHEBI:17158
Term: methylglyoxal
Definition: A 2-oxo aldehyde derived from propanal.
Chemical ID: MESH:D011765
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gpx1increases expressionISOGpx1 (Rattus norvegicus)6480464CTDPyruvaldehyde results in increased expression of GPX1 mRNAPMID:28919305
Gpx1multiple interactionsISOGpx1 (Rattus norvegicus)6480464CTDmagnolol promotes the reaction [Pyruvaldehyde results in increased expression of GPX1 mRNA]; pimagedine inhibits the reaction [Pyruvaldehyde results in increased expression of GPX1 mRNA]PMID:28919305
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