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GENE - TERM ANNOTATION REPORT

RGD ID: 10657
Species: Mus musculus
RGD Object: Gene
Symbol: Glrb
Name: glycine receptor, beta subunit
Acc ID: GO:0060012
Term: synaptic transmission, glycinergic
Definition: The vesicular release of glycine from a presynapse, across a chemical synapse, the subsequent activation of glycine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
Definition Source(s): GOC:dos
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Glrb ISOGlrb (Rattus norvegicus)9068941RGD PMID:15574743 REF_RGD_ID:1598572
Glrbinvolved_inIBAPANTHER:PTN002707984 or MGI:95751 or Glrb (Rattus norvegicus)2290270GO_Central GO_REF:0000033
Glrbacts_upstream_of_or_withinIMP 2290270MGI PMID:1338094

PMID:1338094
Glrbacts_upstream_of_or_withinIMPMGI:18563632290270MGI PMID:12809985 PMID:16672662

PMID:12809985 PMID:16672662
Glrbinvolved_inISOGlrb (Rattus norvegicus)2290270MGI GO_REF:0000096 MGI:4417868
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