GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Fshb | affects expression | EXP | | 6480464 | CTD | bisphenol A affects the expression of FSHB mRNA | PMID:22875908 | Fshb | decreases expression | EXP | | 6480464 | CTD | bisphenol A results in decreased expression of FSHB protein | PMID:32407858 PMID:38021376 | Fshb | decreases secretion | EXP | | 6480464 | CTD | bisphenol A results in decreased secretion of FSHB protein | PMID:28393075 PMID:32488702 | Fshb | increases expression | EXP | | 6480464 | CTD | bisphenol A results in increased expression of FSHB mRNA | PMID:21182934 PMID:24532816 | Fshb | multiple interactions | EXP | | 6480464 | CTD | [bisphenol A co-treated with Diethylhexyl Phthalate] results in decreased expression of FSHB mRNA; [bisphenol A co-treated with Diethylhexyl Phthalate] results in decreased secretion of FSHB protein; Drugs, Chinese Herbal inhibits the reaction [bisphenol A results in decreased secretion of FSHB protein]; KISS1 protein inhibits the reaction [bisphenol A results in decreased expression of FSHB protein] | PMID:22828881 PMID:32407858 PMID:32488702 | Fshb | affects expression | ISO | Fshb (Rattus norvegicus) | 6480464 | CTD | bisphenol A affects the expression of FSHB mRNA | PMID:25181051 | Fshb | decreases expression | ISO | Fshb (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in decreased expression of FSHB mRNA; bisphenol A results in decreased expression of FSHB protein | PMID:19837096 PMID:23554804 PMID:27539358 PMID:31063457 PMID:31424294 PMID:31697385 PMID:35465754 | Fshb | decreases secretion | ISO | Fshb (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in decreased secretion of FSHB protein | PMID:25575453 PMID:28959593 PMID:34973380 | Fshb | increases expression | ISO | Fshb (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in increased expression of FSHB mRNA; bisphenol A results in increased expression of FSHB protein | PMID:19782717 PMID:25575453 PMID:27296223 PMID:28641706 PMID:33967032 PMID:34973380 | Fshb | multiple interactions | ISO | Fshb (Rattus norvegicus) | 6480464 | CTD | [4-nonylphenol results in increased susceptibility to bisphenol A] which results in increased secretion of FSHB protein; bisphenol A promotes the reaction [FSHB protein results in increased expression of STAR mRNA]; Fluvastatin inhibits the reaction [bisphenol A results in decreased expression of FSHB protein]; Fluvastatin promotes the reaction [taxifolin inhibits the reaction [bisphenol A results in decreased expression of FSHB protein]]; taxifolin inhibits the reaction [bisphenol A results in decreased expression of FSHB protein]; taxifolin promotes the reaction [Fluvastatin inhibits the reaction [bisphenol A results in decreased expression of FSHB protein]] | PMID:28859904 PMID:30228064 PMID:35465754 | Fshb | multiple interactions | ISO | FSHB (Homo sapiens) | 6480464 | CTD | [FLG gene mutant form affects the susceptibility to bisphenol A] which results in decreased secretion of FSHB protein; bisphenol A inhibits the reaction [FSHB results in increased expression of CYP19A1 mRNA]; bisphenol A inhibits the reaction [FSHB results in increased expression of CYP19A1 protein]; bisphenol A inhibits the reaction [FSHB results in increased expression of IGF1 mRNA]; bisphenol A inhibits the reaction [FSHB results in increased secretion of Estradiol] | PMID:20064783 PMID:30245359 | |
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