GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Fosl2 | multiple interactions | EXP | | 6480464 | CTD | [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOSL2 protein; [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOSL2 protein; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOSL2 protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOSL2 protein] | PMID:15056714 | Fosl2 | decreases expression | ISO | FOSL2 (Homo sapiens) | 6480464 | CTD | Cocaine results in decreased expression of FOSL2 protein | PMID:15814102 | Fosl2 | multiple interactions | ISO | FOSL2 (Homo sapiens) | 6480464 | CTD | Cocaine promotes the reaction [JUN protein binds to FOSL2 protein] | PMID:15814102 | | ||||||||||||||||||||||
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