GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Fos | multiple interactions | EXP | | 6480464 | CTD | [Aluminum co-treated with Copper] inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the localization of FOS protein] | PMID:23690655 | Fos | decreases expression | ISO | Fos (Rattus norvegicus) | 6480464 | CTD | Copper results in decreased expression of FOS mRNA | PMID:30556269 | Fos | decreases expression | ISO | FOS (Homo sapiens) | 6480464 | CTD | Copper results in decreased expression of FOS mRNA | PMID:16246896 PMID:16391388 | Fos | increases expression | ISO | Fos (Rattus norvegicus) | 6480464 | CTD | Copper deficiency results in increased expression of FOS mRNA; Copper results in increased expression of FOS mRNA | PMID:22465980 PMID:26033743 | Fos | multiple interactions | ISO | FOS (Homo sapiens) | 6480464 | CTD | [Chelating Agents binds to Copper] which results in increased expression of FOS mRNA; [Disulfiram binds to Copper] which results in decreased expression of FOS mRNA; [NSC 689534 binds to Copper] which results in increased expression of FOS mRNA; [Organoselenium Compounds binds to Copper] which results in increased expression of FOS mRNA; Copper promotes the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]] | PMID:17032174 PMID:20971185 PMID:24690739 PMID:25167922 PMID:30911355 | | ||||||||||||||||||||||
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