GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Fos | increases expression | EXP | | 6480464 | CTD | Cadmium results in increased expression of FOS mRNA | PMID:22666406 | Fos | multiple interactions | EXP | | 6480464 | CTD | [Cadmium co-treated with TNFSF11 protein co-treated with CSF1R protein] affects the expression of FOS mRNA; [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of FOS mRNA | PMID:31904401 PMID:32522522 | Fos | affects methylation | ISO | Fos (Rattus norvegicus) | 6480464 | CTD | Cadmium affects the methylation of FOS gene | PMID:21449042 | Fos | decreases expression | ISO | FOS (Homo sapiens) | 6480464 | CTD | Cadmium results in decreased expression of FOS mRNA | PMID:16439709 | Fos | increases expression | ISO | Fos (Rattus norvegicus) | 6480464 | CTD | Cadmium results in increased expression of FOS mRNA | PMID:24236210 | Fos | increases expression | ISO | FOS (Homo sapiens) | 6480464 | CTD | Cadmium results in increased expression of FOS mRNA; Cadmium results in increased expression of FOS protein | PMID:10711420 PMID:11032763 PMID:11738272 PMID:14499349 PMID:17125913 PMID:21120746 PMID:21694771 PMID:22562489 PMID:31646340 | Fos | increases phosphorylation | ISO | FOS (Homo sapiens) | 6480464 | CTD | Cadmium results in increased phosphorylation of FOS protein | PMID:26514923 | Fos | multiple interactions | ISO | Fos (Rattus norvegicus) | 6480464 | CTD | [Cycloheximide co-treated with Cadmium] results in increased expression of FOS mRNA; Dactinomycin inhibits the reaction [[Cycloheximide co-treated with Cadmium] results in increased expression of FOS mRNA] | PMID:1696944 | Fos | multiple interactions | ISO | FOS (Homo sapiens) | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cadmium results in increased phosphorylation of FOS protein]; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of FOS mRNA; Cadmium promotes the reaction [[ESR1 protein binds to JUN protein binds to FOS protein] which binds to CXCL12 promoter]; Cadmium promotes the reaction [ESR1 protein binds to JUN protein binds to FOS protein]; Cadmium promotes the reaction [FOS protein binds to CCND1 promoter]; Cadmium promotes the reaction [FOS protein binds to CXCL12 promoter]; Cadmium promotes the reaction [FOS protein binds to MYC promoter]; Fulvestrant inhibits the reaction [Cadmium results in increased expression of FOS mRNA] | PMID:17125913 PMID:24015267 PMID:26514923 PMID:36602393 | | ||||||||||||||||||||||
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