GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Fn1 | affects expression | EXP | | 6480464 | CTD | Carbon Tetrachloride affects the expression of FN1 mRNA | PMID:17484886 | Fn1 | decreases expression | EXP | | 6480464 | CTD | Carbon Tetrachloride results in decreased expression of FN1 mRNA | PMID:32659284 | Fn1 | increases expression | EXP | | 6480464 | CTD | Carbon Tetrachloride results in increased expression of FN1; Carbon Tetrachloride results in increased expression of FN1 mRNA; Carbon Tetrachloride results in increased expression of FN1 protein | PMID:16508911 PMID:16539848 PMID:20821823 PMID:27477297 PMID:31919559 PMID:37573684 | Fn1 | multiple interactions | EXP | | 6480464 | CTD | alisol B 23-acetate inhibits the reaction [Carbon Tetrachloride results in increased expression of FN1 mRNA]; Bee Venoms inhibits the reaction [Carbon Tetrachloride results in increased expression of FN1]; Colchicine inhibits the reaction [Carbon Tetrachloride results in increased expression of FN1 mRNA]; IL10 protein inhibits the reaction [Carbon Tetrachloride results in increased expression of FN1 mRNA]; NFE2L2 protein promotes the reaction [tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of FN1 mRNA]]; NFE2L2 protein promotes the reaction [tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of FN1 protein]]; PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of FN1 mRNA]; tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of FN1 mRNA]; tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of FN1 protein] | PMID:16539848 PMID:18038451 PMID:20821823 PMID:27477297 PMID:37573684 | Fn1 | affects expression | ISO | Fn1 (Rattus norvegicus) | 6480464 | CTD | Carbon Tetrachloride affects the expression of FN1 mRNA | PMID:16239168 | Fn1 | increases expression | ISO | Fn1 (Rattus norvegicus) | 6480464 | CTD | Carbon Tetrachloride results in increased expression of FN1 protein | PMID:15030980 PMID:17631135 | Fn1 | multiple interactions | ISO | Fn1 (Rattus norvegicus) | 6480464 | CTD | Dexamethasone inhibits the reaction [Carbon Tetrachloride results in increased expression of FN1 protein]; IFNG protein inhibits the reaction [Carbon Tetrachloride results in increased expression of FN1 protein]; Lipopolysaccharides inhibits the reaction [Carbon Tetrachloride results in increased expression of FN1 protein]; TGFB1 protein promotes the reaction [Carbon Tetrachloride results in increased expression of FN1 protein] | PMID:15030980 | Fn1 | multiple interactions | ISO | FN1 (Homo sapiens) | 6480464 | CTD | [Medroxyprogesterone Acetate co-treated with Carbon Tetrachloride] results in increased expression of FN1 protein | PMID:1465320 | | ||||||||||||||||||||||
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