Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10579
Species: Mus musculus
RGD Object: Gene
Symbol: Fgf9
Name: fibroblast growth factor 9
Acc ID: CHEBI:17026
Term: progesterone
Definition: A C21-steroid hormone in which a pregnane skeleton carries oxo substituents at positions 3 and 20 and is unsaturated at C(4)-C(5). As a hormone, it is involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species.
Chemical ID: MESH:D011374
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fgf9decreases expressionEXP 6480464CTDProgesterone results in decreased expression of FGF9 mRNAPMID:22238285
Fgf9multiple interactionsISOFGF9 (Homo sapiens)6480464CTD[FGF9 protein co-treated with FSHB protein] affects the abundance of Progesterone; [Progesterone co-treated with Estradiol] results in decreased expression of FGF9 mRNA; FGF9 protein inhibits the reaction [[IGF1 protein co-treated with FSHB protein] results in increased abundance of Progesterone]; FGF9 protein inhibits the reaction [IGF1 protein promotes the reaction [Bucladesine results in increased abundance of Progesterone]]; FGF9 protein inhibits the reaction [IGF1 protein promotes the reaction [Colforsin results in increased abundance of Progesterone]]; FGF9 protein inhibits the reaction [IGF1 protein results in increased abundance of Progesterone]; FGF9 protein promotes the reaction [Bucladesine results in increased abundance of Progesterone]PMID:17404688 PMID:22798350
Go Back to source page   Continue to Ontology report