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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10579
Species: Mus musculus
RGD Object: Gene
Symbol: Fgf9
Name: fibroblast growth factor 9
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fgf9increases expressionISOFGF9 (Homo sapiens)6480464CTDEstradiol results in increased expression of FGF9 mRNA; Estradiol results in increased expression of FGF9 proteinPMID:12072406 PMID:14602803 PMID:21098263
Fgf9multiple interactionsISOFGF9 (Homo sapiens)6480464CTD[FGF9 protein co-treated with FSHB protein] affects the abundance of Estradiol; [Progesterone co-treated with Estradiol] results in decreased expression of FGF9 mRNA; FGF9 protein inhibits the reaction [[IGF1 protein co-treated with FSHB protein] results in increased abundance of Estradiol]; FGF9 protein inhibits the reaction [Bucladesine promotes the reaction [IGF1 protein results in increased abundance of Estradiol]]; FGF9 protein inhibits the reaction [Colforsin promotes the reaction [IGF1 protein results in increased abundance of Estradiol]]; FGF9 protein inhibits the reaction [IGF1 protein results in increased abundance of Estradiol]PMID:17404688 PMID:22798350
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