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GENE - TERM ANNOTATION REPORT

RGD ID: 10552
Species: Mus musculus
RGD Object: Gene
Symbol: Esr2
Name: estrogen receptor 2 (beta)
Acc ID: DOID:0060224
Term: atrial fibrillation
Definition: A heart conduction disease that is characterized by uncoordinated electrical activity in the heart's upper chambers (the atria), which causes the heartbeat to become fast and irregular and has symptoms palpitations, weakness, fatigue, lightheadedness, dizziness, confusion, shortness of breath and chest pain. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Atrial_fibrillation "DO" "DO", http://www.mayoclinic.org/diseases-conditions/atrial-fibrillation/basics/definition/con-20027014 "DO" "DO", http://www.nhlbi.nih.gov/health/health-topics/topics/af "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Esr2 ISOESR2 (Homo sapiens)11554173CTDCTD Direct Evidence: marker/mechanismPMID:30061737
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