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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10552
Species: Mus musculus
RGD Object: Gene
Symbol: Esr2
Name: estrogen receptor 2 (beta)
Acc ID: CHEBI:88542
Term: Butylparaben
Definition: null
Chemical ID: MESH:C038091
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Esr2affects bindingISOEsr2 (Rattus norvegicus)6480464CTDbutylparaben binds to ESR2 proteinPMID:20132880
Esr2affects bindingISOESR2 (Homo sapiens)6480464CTDbutylparaben binds to ESR2 proteinPMID:11193391
Esr2decreases expressionISOEsr2 (Rattus norvegicus)6480464CTDbutylparaben results in decreased expression of ESR2 mRNAPMID:18648085
Esr2increases expressionISOEsr2 (Rattus norvegicus)6480464CTDbutylparaben results in increased expression of ESR2 mRNAPMID:26888303
Esr2increases expressionISOESR2 (Homo sapiens)6480464CTDbutylparaben results in increased expression of ESR2 mRNA; butylparaben results in increased expression of ESR2 proteinPMID:25128701
Esr2multiple interactionsISOESR2 (Homo sapiens)6480464CTDbutylparaben binds to and results in increased activity of ESR2 proteinPMID:23567241
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