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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10552
Species: Mus musculus
RGD Object: Gene
Symbol: Esr2
Name: estrogen receptor 2 (beta)
Acc ID: CHEBI:63919
Term: 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanol
Definition: A fluorotelomer alcohol that is ethanol substituted at position 2 by a perfluorooctyl group.
Chemical ID: MESH:C033729
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases activityISORGD:692136480464CTD1H, 1H, 2H, 2H-perfluorodecanol results in increased activity of ESR2 protein

PMID:17603182
multiple interactionsISORGD:692136480464CTD1H, 1H, 2H, 2H-perfluorodecanol promotes the reaction [ESR2 protein binds to NCOA2 protein]

PMID:17603182
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.