Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	10551
Species:	Mus musculus
RGD Object:	Gene
Symbol:	Esr1
Name:	estrogen receptor 1 (alpha)

Acc ID:	CHEBI:38940
Term:	sunitinib
Definition:	A pyrrole that has formula C22H27FN4O2.
Chemical ID:	MESH:C473478

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Esr1	increases expression	ISO	ESR1 (Homo sapiens)	6480464	CTD	Sunitinib results in increased expression of ESR1 mRNA	PMID:31533062

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.